Depression an Adverse Effect in One-Third of Prescription Medications

Depression an Adverse Effect in One-Third of Prescription Medications

Depression an Adverse Effect in One-Third of Prescription Medications

Researchers from the University of IL at Chicago discovered that polypharmacy, or taking multiple prescription drugs at once, can increase the risk of depression in United States adults.

"That's compared to about a 15 percent risk of depression if you were taking three or more drugs that had depression listed as a side effect".

The researchers, from the University of IL at Chicago, looked at how more than 26,000 people from 2005 to 2014 used medications.

These common drugs include birth control and hormonal pills, blood pressure and heart medications, proton pump inhibitors, painkillers, and even the simple antacids.

Researchers found adults using multiple medications were more likely to admit to having depression.

"It was both surprising and worrisome to see how any medications have depression or suicidal symptoms as a side effect, given the burden of depression and suicide rates in the country, said Dima Mazen Qato, an assistant professor and pharmacist at the University of IL at Chicago and lead author of the study".

A team of researchers from the University of IL at Chicago discovered that over 200 general medications put up for sale in the United States contribute depression condition as possible undesirable effect. The overall estimated prevalence was 37.2% for use of medications with depression as an adverse effect, which increased from 35.0 to 38.4% from 2005-2006 to 2013-2014.

"People are not only increasingly using these medicines alone, but are increasingly using them simultaneously, yet very few of these drugs have warning labels, so until we have public or system-level solutions, it is left up to patients and health care professionals to be aware of the risks", Dr. Qato said in the statement. Often, patients have several medicines prescribed by multiple doctors, increasing the potential for them to take drug combinations with unsafe side effects. Depression is potentially one of these problems.


More and more Americans are using such prescription drugs, according to the study published this week in the journal JAMA.

Researchers at the University of Illinois: Chicago and Columbia University looked at 26,000 adults' medication habits, among other health issues.

When screening for depression, physicians may consider evaluating medications, she said.

The research is the first to show that these drugs are often used concurrently and that concurrent use, called polypharmacy, is linked to an increased risk of depression. Sometimes another drug can be prescribed.

But study authors say the results do not prove meds with depression as a possible side effect actually cause depression or increase suicide risk.

And almost 5 percent of US adults are estimated to have depression symptoms.

AUBREY: And he says you can talk to your doctor about stopping a medication.

"It was previously thought that a "predisposition" i.e. a history of mood disorders would make a person susceptible for experiencing a depression side effect", Spelsburg, who wasn't involved in the study, said by email.

Noticias relacionadas



[an error occurred while processing the directive]